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Safe and effective long-term treatments that reduce the need for corticosteroids are needed for Crohn's disease. Although purine antimetabolites are moderately effective for maintenance of remission ...


Combined immunosuppression therapy is more effective than conventional treatment using corticosteroids for inducing remission in and management of patients recently diagnosed with Crohn’s disease. Usi ...


A Phase III trial ( PRECiSE 1 ) data have demonstrated that when compared with placebo, a significantly greater proportion of moderate to severe Crohn's disease patients achieved clinical response wit ...


A study has shown that the proton pump inhibitor Esomeprazole ( Nexium ) maintains normal gastric acid levels in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. ...


Mayo Clinic Cancer Center has begun three clinical studies looking at the use of nonsteroidal anti-inflammatory drugs ( NSAIDs ) to prevent cancer ( colon, esophageal or lung ). These studies are part ...


Proton pump inhibitors ( PPIs ) are used for the treatment of acid-related diseases such as gastro esophageal reflux disease ( GERD ). A study found that proton pump inhibitors are associated with a ...


Researchers have discovered what may be a successful non-dietary therapy for celiac sprue, an inherited inflammatory disorder of the small intestine that impacts an estimated 1 in 200 people around th ...


A new enzyme originally developed for commercial food processing turns out to also quickly and nearly-completely break down whole gluten molecules as well as the T cell stimulatory peptides that cause ...


Most people experience occasional heartburn. But when heartburn is severe or occurs frequently over an extended period of time, it is called Gastroesophageal Reflux Disease or GERD. Over time, untreat ...


Researchers found evidence that suggests Crohn's disease is caused by a weak immune response. The study, published in The Lancet, also suggest that Sildenafil ( Viagra ) might help in the treatment o ...


A study found that the risk of infertility in women triples after the most major surgery for the inflammatory bowel disease ulcerative colitis. The authors base their finding on a detailed analysi ...


A small study suggests that chewing gum after colon surgery may speed the return of normal bowel function and shorten patients' hospital stays. . Any type of abdominal surgery can cause ileus, a ma ...


The results from a study showing patients with moderate to severely active Crohn's disease treated with Adalimumab ( Humira ) were more likely to maintain clinical remission through one year than pati ...


Two studies, published in the Clinical Gastroenterology and Hepatology, have showen that prescription painkillers are effective in easing the pain of patients with dormant inflammatory bowel disease ( ...


Researchers at UT Southwestern Medical Center have discovered that a protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with ...