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The association between fibromyalgia and autoimmune diseases has been widely reported in literature. Coeliac disease is a small intestine immune-mediated disorder triggered by gluten ingestion in gene ...


Vedolizumab ( Entyvio ) is a humanized version of Act-1, a murine antibody originally developed in the 1980s with activity against the alpha4beta7-integrin heterodimer. During leukocyte extravasation ...


Takeda Pharmaceutical has announced top-line results from the international, randomized, placebo-controlled, double-blind GEMINI II pivotal phase 3 trial. The trial has evaluated Vedolizumab in 1,11 ...


Rifaximin ( Normix, Xifaxan ) has been used successfully for the prevention of travelers' diarrhea ( TD ), the most general cause of disability among international travelers to developing tropical and ...


Crohn’s disease and ulcerative colitis are chronic, relapsing inflammatory disorders of the gastrointestinal ( GI ) tract. In both Crohn’s disease and ulcerative colitis, leukocytic infiltration of th ...


Safe, effective treatment options exist for patients with mild-to-moderate Crohn’s disease or ulcerative colitis. However, a significant proportion of patients with moderate-to-severe Crohn’s disease ...


Immune responses are capable of killing tumors before they can be directed toward normal body tissue.The findings are published in Cancer Research.There are extremely precise mechanistic methods augme ...


Even the lowest possible dose Acetylsalicylic acid ( 75 mg; Aspirin ) can ward off bowel cancer, if taken regularly.This protective effect is apparent after just one year and in the general population ...


Gilead has informed all healthcare professionals involved in the management of chronic hepatitis B on important renal safety information and recommendations in the current European Summary of Produc ...


Novel chemotherapy and biological agents for metastatic colorectal cancer, combined with surgical advances in liver resection, have resulted in a dramatic increase in survival for patients with adva ...


Safe and effective long-term treatments that reduce the need for corticosteroids are needed for Crohn's disease. Although purine antimetabolites are moderately effective for maintenance of remission ...


Combined immunosuppression therapy is more effective than conventional treatment using corticosteroids for inducing remission in and management of patients recently diagnosed with Crohn’s disease. Usi ...


A Phase III trial ( PRECiSE 1 ) data have demonstrated that when compared with placebo, a significantly greater proportion of moderate to severe Crohn's disease patients achieved clinical response wit ...


A study has shown that the proton pump inhibitor Esomeprazole ( Nexium ) maintains normal gastric acid levels in patients with Zollinger-Ellison syndrome or idiopathic gastric acid hypersecretion. ...


Mayo Clinic Cancer Center has begun three clinical studies looking at the use of nonsteroidal anti-inflammatory drugs ( NSAIDs ) to prevent cancer ( colon, esophageal or lung ). These studies are part ...