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Travellers' diarrhoea causes substantial acute and long-term morbidity. Chemoprophylaxis with fluoroquinolones or Rifaximin ( Normix, Xifaxan ) is effective in prevention of diarrhoea in individuals t ...


A systematic review and meta-analysis of data from randomized controlled trials ( RCTs ) to evaluate the efficacy and safety of Certolizumab pegol ( Cimzia ) was performed. A total of five RCTs, in ...


Whether sequential treatment can replace triple therapy as the standard treatment for Helicobacter pylori infection is unknown.The efficacy of sequential treatment for 10 days and 14 days with triple ...


The efficacy of Vedolizumab ( Entyvio ), an alpha4beta7 integrin antibody, in Crohn's disease is unknown.In an integrated study with separate induction and maintenance trials, researchers have assesse ...


The hemoglobin threshold for transfusion of red cells in patients with acute gastrointestinal bleeding is controversial. Researchers have compared the efficacy and safety of a restrictive transfusion ...


Results of the phase II, randomized, double-blind, placebo-controlled RECAP trial of Ruxolitinib ( Jakafi ), its oral JAK1 and JAK2 inhibitor, in combination with Capecitabine ( Xeloda ) in patients w ...


Bayer HealthCare has announced that the European Commission has approved Stivarga ( Regorafenib ) tablets for the treatment of adult patients with metastatic colorectal cancer ( mCRC ) who have previo ...


Aspirin ( Acetylsalicylic acid ) is known to lower risk for some cancers, and a new study led by a UC San Francisco researcher, Carlo Maley, points to a possible explanation, with the discovery that A ...


Final data from IMPACT study provide proof of principle for new treatment approach. The findings confirm the biological action of the drug called MGN1703 and suggest it may be possible to identify whi ...


There are no agents specifically approved in the United States or European Union for advanced gastric cancer patients. Gastric cancer is the fourth most common cancer in the world and the second-leadi ...


PAVES ( Pegfilgrastim and Anti-VEGF Evaluation Study ) trial has evaluated Pegfilgrastim ( Neulasta ) in 845 patients receiving FOLFOX or FOLFIRI and Bevacizumab ( Avastin ) for the first-line treatme ...


The chance of ending up in a nursing facility appears to be significantly lower for older patients who undergo a laparoscopic procedure than for those who have open surgical resection for colon cancer ...


In an analysis of the results of interventions to eradicate the bacterium Helicobacter pylori ( a risk factor for gastric cancer ) in seven diverse community populations in Latin America, researchers ...


Numerous epidemiologic studies have shown that a diet high in salt is associated with an increased risk of gastric cancer. Timothy L. Cover and colleagues of Vanderbilt University have shown that high ...


In two large studies, the association between Acetylsalicylic acid ( Aspirin ) use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular Aspirin use associated with a l ...