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In pediatric Crohn's disease, fat mass improves over time with treatment, but lean mass deficits persist. This observational study of the associations of physical activity and dietary intake wi ...


Vitamin and iron deficiencies are common in patients with inflammatory bowel disease ( IBD ) as a result of chronic intestinal inflammation, increase in demand, or dietary restrictions. Researcher ...


The U.S. Food and Drug Administration ( FDA ) has approved Keytruda ( Pembrolizumab ), an anti-PD-1 therapy, for the treatment of patients with recurrent locally advanced or metastatic gastric or gast ...


Agents that induce an immune response against tumors by altering T-cell regulation have increased survival times of patients with advanced-stage tumors, such as melanoma or lung cancer. Researcher ...


Researchers have found early evidence that a common but harmless virus could be behind the celiac disease, by causing the immune system to turn against gluten. Up until now, research has mainly foc ...


Pembrolizumab ( Keytruda ) has shown a promising response rate in patients with pretreated metastatic gastric cancer, according to results from the KEYNOTE-059 trial presented at the ESMO 2017 Congres ...


Vedolizumab ( Entyvio ) is a gut-selective antibody to alpha4beta7 integrin for the treatment of ulcerative colitis and Crohn's disease. An integrated summary of the safety of Vedolizumab was reported ...


Data from a randomized, double-blind, multicenter, exploratory phase 1b study evaluating the effects of investigational oral GED-0301 ( Mongersen ) 160 mg on both endoscopic response and clinical remi ...


Interim topline data from a randomized, double-blind, multicenter, exploratory phase 1b study evaluating the effects of oral Mongersen ( GED-0301 ) on both endoscopic and clinical outcomes in patients ...


Clostridium difficile infection ( CDI ) is the leading cause of antibiotic-associated diarrhea. Clostridium difficile infection has increased in incidence and severity over the past decade, and is a g ...


Recurrent Clostridium difficile infection ( rCDI ) contributes to a significant burden of disease in patients with inflammatory bowel disease ( IBD ). In the RECIDIVISM study, researchers have sough ...


Proton pump inhibitors ( PPIs ) have been associated with adverse clinical outcomes amongst Clopidogrel ( Plavix ) users after an acute coronary syndrome. Recent pre-clinical results suggest that th ...


Favourable efficacy and safety profiles for Simeprevir ( Olysio ) in combination with Pegylated interferon alpha ( PEG-IFN alpha ) and Ribavirin ( triple therapy ) have been shown in clinical trials. ...


Infliximab ( Remicade ) has been shown to have beneficial effects on bone metabolism in patients with Crohn's disease ( CD ) although as yet the exact mechanisms have not been fully elucidated. A s ...


Endoscopic healing and clinical remission are important parameters to evaluate therapeutic efficacy in Crohn's disease. The aim of a study was to investigate the clinical effectiveness of Adalimumab ...